Oxidative stress in dogs during mid-gestation abortion: Fetal and maternal antioxidant alterations with clinical and hematological features

The present study aimed to evaluate the GSH and MDA levels in dog’s serum vital organs of aborted fetuses, after application two abortifacient. Animals group I (n = 6) were treated twice with subcutaneous injection 10 mg/kg aglepristone II 3) received prostaglandin F2α at a dose 125 μg/kg every 12 hours until abortion process completed. Hematologic examinations sedimentation rates performed bitches. duration between first occurrence vaginal discharge expulsion fetuses ranged 14-29 (mean: 22.6±5.5 h) 24-33 II, respectively. Both treatments significantly increased (P<0.01); however throughout study, enhanced plasma only on day 1. lower aglepristone-treated bitches than prostaglandin-treated animals (P<0.05). resulted similar liver heart tissues (P>0.05). kidney, muscle did not differ groups (P>0.05), reduced tissue High could be evaluated as useful marker for fetal suffering pregnancy controls. levels, measured suggest possible toxic effects abortifacients newborns, both medical agents are being used parturition induction.